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Alpha 2 Macroglobulin (A2M)

A New Treatment For Arthritis

A2M is becoming a valuable asset in our regenerative medicine arsenal and an important part of our program for the restoration of joints, prevention of knee and other joint arthritis and the treatment of low back pain. Along with our successful stem cell injections, we are using A2M injections in order to maximize the natural healing properties of the blood to improve overall patient outcomes.

Macroglobulin, or A2M injection therapy, uses proven scientific techniques and natural healing methods to successfully treat osteoarthritis at its source. It is used to prevent cartilage breakdown, promotes tissue growth and support the overall restoration of an affected joint.

alpha 2 macroglobulin

The Science

Alpha 2 Macroglobulin is made in the liver and occurs naturally in blood plasma. A2M uses specific binding sites to snare bad enzymes that destroy cartilage. Once each binding site has trapped the enzymes, both the A2M and the bound enzymes are disposed of naturally by the body. This is a function known as “suicide inhibition.”
Scientific evidence points to A2M to be the key to stopping osteoarthritis at the molecular level. A2M is a Broad-Spectrum Multi-Purpose Protease Inhibitor (powerful chemical that destroys the proteins that lead to arthritis) that captures and inactivates the three major chemicals that lead to joint breakdown and cartilage damage. Once these bad chemicals are trapped by A2M, the body can then quickly eliminate them.

Some scientific studies have concluded: A2M is a plasma protease inhibitor that is not present in sufficient concentrations to inactivate the chemicals that found in high concentrations in patients with Osteoarthritis. It has been suggested that supplemental intra-articular A2M provides protection for post traumatic OA.

A2M In North Brunswick, New Jersey

Dr. Magaziner utilizes a special Alpha 2 Macroglobulin concentrator that are not commonly seen in other practices. By collecting approximately 100cc’s of the patient’s blood and processing it through a multi-phase centrifugation and filtration system, a concentrated volume of A2M can be collected. This special, patented system selectively super concentrates A2M. The A2M produced by the concentrator can then be used for treatment inside of joints, degenerative discs, and into damaged soft tissues and areas of inflammation. Individual results may vary from patient to patient.

For more information on A2M contact our office.

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